The following list provides subject specification and content studied during Key Stage 4 at The Radclyffe School.
| AQA GCSE | |
| Art (Fine Art) | 8202 |
| Art (Photography) | 8206 |
| Biology | 8461 |
| Chemistry | 8462 |
| Combined Science | 8464 |
| Drama | 8261 |
| English Language | 8700 |
| English Literature | 8702 |
| Food Preparation & Nutrition | 8585 |
| Geography | 8035 |
| Music | 8271 |
| Physics | 8463 |
| Religious Studies A | 8062MA |
|
Edexcel – GCSE |
|
| Business Studies | 1BS0 |
| Design & Technology | 1DT0 |
| French | 1FR0 |
| History (11, 25, & 31) | 1HI0F5 |
| Maths | 1MA1 |
| Spanish | 1SP0 |
| Statistics | 1STO |
| Level 3 Algebra | AAL30 |
|
OCR – GCSE |
|
| Computer Science | J276 |
| P.E. | J587 |
|
WJEC – GCSE |
|
| English Language | C700QS |
| English Literature | C720QS |
| Media Studies | C680QS |
|
OCR – ELC |
|
| Science | R591B |
|
Edexcel – BTEC Level 1 & 2 First Award/DIDA |
|
| Level 1 and 2 Tech Award in Performing Arts (603 0406 6) |
YPN38 |
|
NCFE |
|
| Level 2 Technical Award in Music Technology | (601 6774 9) |
|
OCR Nationals |
|
| National Award in Sports Studies | J803 |
| National Certificate in Sports Studies | J813 |
| National Award in Creative iMedia | J807 |
| National Certificate in Creative iMedia | J817 |
| National Certificate in Information Technologies | J808 |
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